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Holderite There

Callas's Twist is a condition combining abnormal bone growth with muscle degeneracy. It is noticeable in childhood, but debilitating in adolescence when the rate of bone growth accelerates and skeleton density increases. Diagnosing and treating the disease at a young age makes all the difference between death at fifteen and a life forty years long. Treatment is most successful if it begins before adolescent growth, but if that growth starts early--or if the diagnosis comes very late--there is little that can be done without halting the body's development.   Holderite There is a medication that has given hundreds of girls with Callas's Twist the opportunity to grow up.

Utility

Callas's Twist is a tricky disease to manage. Full-body bracing is more effective the earlier it starts, but is too restrictive for small children. An exercise regimen combined with medication and a diet supporting muscular health is recommended for the early years, with the bracing to begin at the first indications of adolescence.   Early maturity is a condition unrelated to Callas's Twist, but co-occurs in a small percentage of patients. Their deterioration accelerates, potentially killing them by the age of ten. Even if they are moved into a brace immediately, they lose the benefit of several years of muscle treatment and live barely as long as normally maturing patients with no treatment.   Hormone suppression was tested on Callas's Twist patients early in the 15th Volcanic century. Those patients consistently matured later, allowing more time for the exercise and muscle treatments to take effect. For patients with an early diagnosis and average stages of growth, that extra time has minimal benefit, giving them perhaps one or two extra years in exchange for five years of treatment.
Discovery
Holderite There is one of a class of compounds developed late in the 13th-14th Volcanic century chemistry boom.
Holderite There is a silly name, but if you're giving it to a young girl fighting a deadly disease, why not call it something that will make her laugh?
Scribe Elan

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