Lycanthropic Parvovirus

The Lycanthropic Parvovirus (LPV) is a zoonotic virus classified in the family Parvoviridae. It is responsible for a condition known as lycanthropy, which causes drastic physiological and psychological changes in its host, transforming them into what are colloquially known as "lycans" or werewolves.   LPV is unique among parvoviruses due to its ability to infect and transform nearly every nucleated cell in the human body. Unlike most parvoviruses, LPV doesn't destroy host cells through lysis but instead buds from them, leaving them altered but intact. This allows the virus to spread rapidly without triggering an immediate immune response.   The virus causes extensive genetic alterations in host cells, leading to dramatic morphological changes that transform the human body into a more canine-like form over a period of about six weeks. These changes are irreversible and affect every major system in the body, including skeletal, muscular, sensory, and neurological.   LPV infection is believed to be the biological basis for werewolf legends found in cultures around the world. While not supernatural in nature, the abilities and limitations of infected individuals often appear to be beyond human capabilities, leading to their mythologization in folklore.

Transmission & Vectors

  • Primarily transmitted to humans via the bite of an infected canine, specifically gray wolves or their subspecies
  • Zoonotic, capable of infecting both canines and primates
  • Unable to infect or be carried by organisms other than canines and primates

Causes

  • Infection by the Lycanthropic Parvovirus (LPV)

Symptoms

Initial (24-48 hours post-infection):
  • Severe thirst
  • High fever
  • Chills
  • Itching
  Progressive (48 hours onward):
  • Rapid hair growth across the body
  • Increased aggression and violence
  • Loss of verbal communication skills
  • Desire for isolation
  Full Transformation (over 6 weeks):
  • Extensive bone and muscle growth
  • Elongation of facial bones forming a canine-like snout
  • Development of claws on hands and feet
  • Changes in dentition, including growth of additional teeth
  • Heightened senses, especially night vision, hearing, and smell
  • Reversal of circadian rhythm
  • Skin color changes (light or dark gray)
  • Eye color changes (pale blue or yellow-amber)
  • Development of plantigrade/digitigrade stance
  • Enlarged internal organs

Treatment

None currently known.

Prognosis

  • Irreversible transformation
  • High mortality rate during transformation process due to strain on the body
  • Survivors experience permanent physical and psychological changes
  • Lifespan of transformed individuals (lycans) not definitively known

Sequela

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  • Permanent physical transformation into lycan form
  • Loss of higher cognitive functions and increased aggression
  • Insatiable appetite and compulsion to hunt/feed
  • Nocturnal behavior
  • Inability to return to human society
  • Hosts & Carriers

    • Primary hosts: Canines (specifically gray wolves and their subspecies) and humans
    • No other known hosts or carriers currently known

    Prevention

    Avoiding contact with potentially infected wolves may reduce transmission risk.

    Epidemiology

    • Originally believed to have emerged in Eurasia
    • Most common in professions with frequent wolf contact (hunters, trappers, lumberjacks)
    • Exact prevalence unknown

    History

    • Believed to have existed for millennia, possibly infecting Neanderthals
    • Closely associated with werewolf legends in various cultures worldwide
    • Scientific study of the virus is relatively recent
    Origin
    Natural
    Rarity
    Uncommon

    Comments

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    Jul 25, 2025 10:48

    Cool I love werewolfs!