Blissful Sleep
Most poisons are incredibly painful and fail to deliver the boon of death to the people fated to live. Where before, the crippling pain caused by a deadly substance was unbearable but fast-lived, the agony now spans until it has completely been eliminated from the organism, which is sometimes never. There has been cases of people hit by a poison so strong they still suffer from it years later, their bodies writhing in pain where the last shreds of their sanity is long gone.
If no chemical is able to grant the cherished death, some are more effective than others at soothing the pain that living is. These poisons, among the rarest, shut down bodily functions and plunge their consumer into a deep, painless sleep. Their means of action differ, but the common point is an induced coma from which it is almost impossible to wake up.
Some of them remain painful at absorption, but then the face muscles relax and the "victim" lays dormant, unaware of the surrounding despair, unfeeling. Blissful Sleep, as it was called, is the closer anyone can get to real death, and thus a state actively sought by many.
However, the amount of the precious substances are limited, especially given that only a few of them were medicinal, the others being considered deadly poison before and thus destroyed on sight. New research is trying to synthesize similar compounds, but the effects on the immortal biology are always unpredictable and only a few brave souls are still willing to play the role of guinea pigs, after what happened to the first failures.
It is collectively believed that blissful sleep might be the replacement for Death, a state in-between, not really dead but not living either. A third state of existence that may be the only way out of this world.
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